Call for Papers: Integrating In Vitro, In Vivo, and In Silico Research
The In-Vitro In-Vivo In-Silico Journal (IIIJ) invites submissions that connect laboratory discovery, living system validation, and computational prediction. We welcome original research, reviews, method papers, and translational studies that demonstrate how evidence moves across the three research domains to inform real world biomedical advances.
In Vitro
Cell, molecular, and biochemical investigations
In Vivo
Animal models and clinical translation
In Silico
Computational models and AI driven insights
Research Themes Across Three Methodologies
In Vitro Themes
Foundational Discovery- Cell signaling, gene expression, and pathway validation
- Organoid and tissue engineering innovations
- Mechanistic assays and biomarker identification
- Drug screening and toxicity studies
In Vivo Themes
Physiological Evidence- Animal model validation and translational endpoints
- Clinical trial design and outcome reporting
- Pharmacokinetics, safety, and dosing strategies
- Comparative studies that bridge lab and clinic
In Silico Themes
Computational Innovation- Predictive modeling and simulation of biological systems
- Machine learning for diagnostics and discovery
- Bioinformatics pipelines and multi omics integration
- Digital twins and virtual screening approaches
What We Publish
Why Publish in IIIJ
IIIJ connects researchers across experimental and computational domains. Our editorial board includes laboratory scientists, clinicians, and computational experts who understand how discoveries progress from cell culture to clinical translation and digital prediction. Publishing here positions your work within a truly integrative scientific community.
Submission Expectations
Manuscripts should describe methodology in enough detail for reproducibility and clearly explain how findings relate across the three research domains. Studies that validate computational predictions with experimental data or translate laboratory findings into clinical insights are strongly encouraged.
Review and Decision Timeline
All submissions undergo editor screening and double blind peer review. We target an initial decision within 21 days, with constructive guidance for revisions. Our reviewers focus on methodological rigor, ethical compliance, and translational relevance.
Special Issues and Themed Collections
IIIJ welcomes proposals for special issues on emerging topics such as organoid modeling, AI driven drug discovery, or in vivo validation of computational biomarkers. Guest editors collaborate with the editorial office to maintain quality and timeline discipline.
Data and Code Transparency
We encourage data availability statements, repository links, and code sharing when applicable. Transparent data practices strengthen reproducibility and improve the utility of your results for other researchers.
Ethics and Compliance
Studies involving human or animal subjects must include ethics approvals and follow relevant reporting standards. For clinical research, include trial registration and informed consent where applicable.
Global Visibility
IIIJ is open access, enabling immediate global reach. Articles are published online with DOI assignment and metadata dissemination to support discovery and citation.
Early Career Submissions
We welcome early career authors and student led projects. Clear methodological reporting and transparent data practices are key to successful submission, regardless of career stage.
Submission Checklist
Before submitting, confirm that your manuscript includes a structured abstract, clear methods, ethics statements, and a data availability statement. Provide figure files and supplementary materials in separate uploads. A complete submission speeds up editorial screening.
Interdisciplinary Emphasis
IIIJ prioritizes work that demonstrates how evidence travels from bench research to living systems and computational prediction. If your study spans multiple methods, explain the integration and the added value of each approach.
Open Access Advantage
Open access publication increases readership and citation potential across disciplines. IIIJ ensures immediate visibility for cross domain research that would otherwise be siloed within separate laboratory, clinical, or computational journals.
Special Issue Opportunities
If your research aligns with a themed collection, indicate the special issue title during submission. Guest editors coordinate review timelines and ensure a cohesive collection that highlights the field.
What Makes a Strong Submission
Successful manuscripts clearly explain how results connect across methods. We value studies that link bench findings with in vivo validation or show how computational models guide experimental design. Provide a concise rationale for the translational impact of your work.
Author Support
If you are unsure about fit or scope, contact the editorial office before submission. Our team can advise on article type selection, data availability expectations, and how to highlight the integrative aspects of your research.
Ethical Readiness
Confirm that ethics approvals, consent statements, and data sharing plans are complete before submission. Strong compliance at the outset reduces delays and improves the review experience.
IIIJ is the home for translational research that connects the lab bench, living systems, and computational models. We invite work that advances the full pathway of discovery.
Submit Your Manuscript Today
Share your integrative research with a global audience. Use ManuscriptZone or our simple submission form to begin the review process. Include a concise cover letter highlighting cross method value and translational relevance. If you are targeting a special issue, mention it in your submission so the manuscript is routed correctly. Submissions are accepted year round, and early submission helps secure timely review. Please include ethics and data statements where applicable. Studies that integrate methods receive strong consideration. Multidisciplinary teams are encouraged for submissions.
