All Articles

Open Access Pub initiated with an aim of promoting the progress and upholding the cause of Science and Technology using the concept of Open Access with the best system ever available along with retaining its Quality" -the main element.

Recently Published Articles

The Combination of Fractionated Erbium:YAG Laser Skin Microporation and Topical Imiquimod Is A New, Safe And Efficient Strategy for the Treatment of Actinic Keratosis and Basal Cell Carcinoma: Report of Two Pilot Studies

Abstract:

Two pilot studies evaluate fractional Er:YAG laser microporation to enhance topical imiquimod delivery for actinic keratosis and basal cell carcinoma. The approach seeks to increase epidermal penetration while limiting systemic exposure. Early results suggest acceptable tolerability and lesion response, supporting larger controlled trials.

...

Read Article

What are the Risk Factors for ≥4500 g Macrosomia?

Abstract:

Objective:

To identify risk factors for ≥4500 g macrosomic babies given that maternal and neonatal complications of macrosomia increase with birth weight.

Design:

Cross sectional analytical study.

Setting:

The Yaoundé University Teaching Hospital and Central Maternity, Cameroon from October 1st, 2012 to June 30th, 2013.

Population:

42 women who delivered ≥4500 g babies and 126 women who delivered babies of 4000 to <4500 g were recruited.

Methods:

Data were analysed using SPSS 18.0. Analyses included the student t-test and the Fisher exact...

Read Article

Pseudotumor Tuberculosis Of Liver: A Rare Entity

Abstract:

We present a rare case of a 46-year-old man who presented with recurrent fever and abdominal pain without other symptoms. Laboratory data were no specific for diagnosis. Abdominal imaging revealed a pseudotumor liver. A diagnosis of isolated liver tuberculosis with abscess component was confirmed with US-guided liver biopsy and histopathological examination. The patient received antibacillous drugs with success.

...

Read Article

Giant Isolated Hydatid Cyst of Spleen

Abstract:

Liver is most commonly involved organ in hydatid cyst. Primary splenic hydatid cysts are rare; we report a case of an isolated giant hydatid cyst of spleen in a 17-year-old man. The diagnosis was confirmed by imaging findings and serology. Partial cystectomy was performed with success. In cystic lesions of spleen, hydatid cyst should be kept in patrician’s mind in the differential diagnosis. Although splenectomy is the gold standard for treating hydatid disease of the spleen, in young patient spleen-preserving surgery seems give good results.

...

Read Article

Acquired Abnormalities of Plasma Von Willebrand Factor Related Parameters and ADAMTS13 Autoantibodies in Aggressive Haematological Malignancies.

Abstract:

Background

Abnormalities of plasma von Willebrand Factor (vWF) system has been described in solid tumors but more information is required to understand the pathophysiological process in haematological malignancies.

Objectives

This study was carried out to investigate the changes in vWF-related parameters including ADAMTS13 protein level in aggressive haematological malignancies and to identify the prevalence of anti-ADAMTS13 antibody as well as its correlations with vWF-related parameters.

Patients/Methods

Patient newly diagnosed or having relapse acute leukaemias or aggresive non-Hodgkin lymphomas were recruited into this study. Exclusion criterias include; pregnancy, patient already commenced chemotherapy, sepsis or has ...

Read Article

Unusual cutaneous toxicity after prolonged use of Hydroxyurea in polycythemia vera: a case report

Abstract:

Hydroxyurea (HU) is commonly used for the long-term treatment of patients with chronic myeloproliferative neoplasms. The drug is usually well tolerated in the large majority of subjects, although systemic and/or localized toxicities have seldom been reported. Here we report a case of unusual cutaneous toxicity due long-term use of HU in a patient with polycythemia vera.

...

Read Article

Haematological Disturbances in Dengue Haemorrhagic Fever - its Pathogenesis and Management Perspectives

Abstract:

Haemorrhage is common to both dengue fever (DF) and dengue haemorrhagic fever (DHF). Thrombocytopaenia is exceedingly common, while prolonged partial thromboplastin time and reduced fibrinogen concentration are the other abnormal haemostatic indices evident from early in the disease course. These haematological abnormalities correlate better with the timing and severity of plasma leakage rather than the clinical haemorrhagic manifestations. Blood products including prophylactic platelet transfusions are hardly required in the management of DHF. Judicious fluid therapy is the most effective intervention to prevent complications and bleeding in DHF. Concealed haemorrhage is an important complication requiring early recognition and blood transfusions to improve outcomes. Understanding the pathogenesis of coagulopathy and the significance of altered haemostatic indices, and its co-relation to disease severity and phase of DHF, is essential for appropriate intervention...

Read Article

Superior Sclera Versus Temporal Corneal on Steep Axis Incision to Correct Pre-Existing Corneal Astigmatism Less Than 1.5 D

Abstract:

Purpose:

Cataract is the leading cause of blindness worldwide. Even in an uneventful cataract surgery, surgically induced astigmatism remains the major hurdle in attaining good unaided visual acuity post surgery. If pre-existing corneal astigmatism is not corrected at the time of surgery, it will result in more postoperative astigmatism; therefore, it is important to correct pre-existing corneal astigmatism.

Material & Methods

In this prospective study, 100 eyes of 100 age and sex matched patient’s with comparable preoperative astigmatism and visual acuity were divided in two groups according to pre operative corneal astigmatism. SIG (superior scleral incision group) included 50 eyes with steeper vertical axis and TIG (temporal corneal incision group) included 50 eyes with steeper horizontal axis. SIG and TIG...

Read Article

Culturally Tailored Nutrition and Lifestyle Intervention can Effectively Reduce the Cardio-Metabolic Risk Factors in Korean Migrants Living in Australia

Abstract:

The risk levels of chronic diseases are increasing among Asian migrants in Western countries compared to their origin-country counterparts. This study evaluates the impact of an 8-week nutrition and lifestyle intervention on cardio-metabolic risk factors in Korean migrants living in Melbourne, Australia. Thirty participants aged 32-62 years completed the program. Self-reported food intake and physical activity, anthropometric and blood pressure measurements, and biomarkers of cardio-metabolic risk were assessed. An initial training session and four consequent nutrition advice sessions were provided for all participants. There was a significant reduction in the waist and hip circumferences. Positive changes were also observed in plasma lipid profiles, calcium intake and frequency of physical activities. These findings demonstrate that a culturally appropriate nutrition and lifestyle intervention can be successfully delivered to reduce the cardio-metabolic risk fact...

Read Article

Breakfast Cereal and Nutrition Education on Body Mass Index and Diet Quality in Elementary School Children: A Pilot Study

Abstract:

Objective:

Skipping breakfast has been associated with an increased risk of obesity. This randomized controlled pilot study tested whether emphasizing breakfast consumption, in conjunction with nutrition counseling, would improve weight status and dietary quality in children.

Design and Methods:

Twenty children were recruited and randomized to a breakfast (BF, n=11) or control (n=9) intervention. Both groups received weekly group nutrition counseling for 12 wk but breakfast consumption was emphasized, and ready-to-eat (RTE) cereal provided, to BF only. Anthropometric measurements were taken weekly. Three-day food records were taken at baseline and endpoint.

Results:

Weight status did not change significantly, however, children...

Read Article