Journal of Spleen And Liver Research

Two Convenient Submission Methods

We offer two streamlined pathways for submitting your hepatology and gastroenterology research. Choose the method that best fits your workflow and manuscript complexity.

Recommended

ManuscriptZone Portal

Our comprehensive manuscript management system designed for complete submission tracking and seamless communication with editors and reviewers.

Real-time submission status tracking
Auto-save functionality prevents data loss
Direct access to reviewer comments and editor decisions
Guided workflow with step-by-step instructions
Secure document upload and version control
Email notifications at every stage

Best for: Complex manuscripts, multi-author submissions, and researchers who want complete visibility into the review process.

Submit via ManuscriptZone

Quick Option

Quick Submission Form

A streamlined, single-page submission form for straightforward manuscripts that don't require extensive metadata or complex file management.

No account registration required
Simple one-page form
Fast submission process (under 10 minutes)
Ideal for case reports and short communications
Automatic transfer to ManuscriptZone for tracking
Email confirmation upon receipt

Best for: Case reports, letters to the editor, and researchers seeking the fastest submission path.

Use Quick Submission Form

First-time submitting? We recommend the ManuscriptZone Portal for its comprehensive guidance and real-time tracking features. Both methods undergo the same rigorous peer review process and receive equal editorial consideration.

Article Types We Publish

The Journal of Spleen and Liver Research welcomes diverse manuscript types that advance our understanding of hepatic and splenic pathophysiology, clinical management, and therapeutic innovations. Each submission undergoes rigorous peer review by experts in hepatology, gastroenterology, and related disciplines.

Original Research Articles

Comprehensive studies on liver disease mechanisms, splenic disorders, hepatocellular carcinoma, cirrhosis pathogenesis, portal hypertension, or novel therapeutic approaches.

• Up to 6,000 words • 21-day review

Clinical Case Reports

Unique presentations of rare hepatic or splenic conditions, unusual disease manifestations, novel diagnostic approaches, or unexpected treatment outcomes in liver disease management.

• Up to 2,500 words • 14-day review

Systematic Reviews & Meta-Analyses

Comprehensive evidence synthesis on hepatology topics including treatment efficacy, diagnostic accuracy, epidemiological trends, or prognostic factors in liver disease.

• Up to 8,000 words • 28-day review

Clinical Trials

Randomized controlled trials, observational studies, or interventional research evaluating treatments for hepatic diseases, liver transplantation outcomes, or splenic disorders.

• Up to 5,000 words • 21-day review

Technical Notes & Methods

Novel surgical techniques for liver resection, innovative diagnostic protocols, laboratory methodologies for hepatic biomarker analysis, or imaging advances in liver disease.

• Up to 3,000 words • 14-day review

Review Articles

Comprehensive overviews of current knowledge in hepatology subspecialties: viral hepatitis, autoimmune liver disease, metabolic liver disorders, or hepatobiliary malignancies.

• Up to 7,000 words • 28-day review

Short Communications

Preliminary findings, pilot studies, or brief reports on emerging hepatology topics, novel observations in liver pathology, or time-sensitive clinical insights.

• Up to 2,000 words • 10-day review

Editorials & Commentaries

Expert perspectives on controversial topics in hepatology, critical appraisals of recent research, or opinion pieces on clinical practice guidelines and liver disease management.

• Up to 1,500 words • 7-day review

Manuscript Preparation: All submissions must follow ICMJE guidelines. Clinical trials require registration in recognized databases (ClinicalTrials.gov, ISRCTN). Animal studies must comply with ARRIVE guidelines. Human studies require ethics committee approval and informed consent documentation.

Peer Review Timeline

We are committed to transparent, efficient peer review that respects your time while maintaining rigorous quality standards. Our editorial team includes hepatologists, gastroenterologists, hepatobiliary surgeons, and liver pathologists who ensure expert evaluation of your work.

Submission Received

Your manuscript is logged into our system and assigned a unique tracking number. You receive immediate email confirmation with submission details and portal access.

Day 0

Initial Editorial Screening

The Editor-in-Chief or Associate Editor reviews your manuscript for scope alignment, technical completeness, and adherence to submission guidelines. Plagiarism screening via iThenticate is performed (similarity index must be below 15% for hepatology research).

Days 1-3

Reviewer Assignment

Manuscripts passing initial screening are assigned to 2-3 expert reviewers specializing in your research area (e.g., viral hepatitis, cirrhosis, hepatocellular carcinoma, liver transplantation). Reviewers are selected based on publication history, expertise match, and absence of conflicts of interest.

Days 4-7

Peer Review Process

Reviewers evaluate scientific rigor, methodological soundness, clinical relevance, and contribution to hepatology literature. They assess study design, statistical analysis, interpretation of results, and adherence to reporting standards (CONSORT, STROBE, PRISMA as applicable).

Days 8-28

Editorial Decision

The handling editor synthesizes reviewer feedback and makes a decision: Accept, Minor Revision, Major Revision, or Reject. You receive detailed reviewer comments, editor recommendations, and clear guidance for revisions if applicable.

Days 29-35

Revision Submission (if required)

Authors submit revised manuscripts with point-by-point responses to reviewer comments. Revised manuscripts are typically returned to the same reviewers for re-evaluation, ensuring consistency in quality assessment.

Author timeline varies

Re-review & Final Decision

Reviewers assess whether revisions adequately address their concerns. The editor makes a final decision based on reviewer recommendations and author responses to feedback.

Days 36-50

Acceptance & Production

Accepted manuscripts enter production for copyediting, typesetting, and final formatting. Authors review proofs and provide final approval before publication. Articles are published online immediately upon completion.

Days 51-60

Publication & Indexing

Your article is published online with a DOI and submitted to PubMed, Scopus, Web of Science, and Google Scholar for indexing. Open access ensures immediate global visibility to the hepatology research community.

Day 60+

Expedited Review Available: Clinical case reports of rare hepatic conditions and short communications on urgent hepatology topics may qualify for expedited review (10-14 days to first decision). Contact the editorial office to request expedited consideration.

Pre-Submission Checklist

Ensure your manuscript meets all requirements before submission to avoid delays in the review process. Complete manuscripts receive faster editorial screening and reviewer assignment.

Required Elements

Manuscript File: Complete manuscript in Word (.docx) or LaTeX format, including title page, abstract (250 words maximum), keywords (5-8 terms), introduction, methods, results, discussion, and conclusions. For clinical studies, include patient demographics and baseline characteristics.
Figures and Tables: High-resolution figures (minimum 300 DPI) in TIFF, EPS, or PNG format. Tables in editable format (Word or Excel). All figures and tables must be cited in the text and include descriptive captions. Histopathology images should include magnification and staining information.
Ethics Documentation: IRB/Ethics committee approval letter for human studies. Animal research must include IACUC approval and ARRIVE checklist compliance. Clinical trials require trial registration number and protocol availability.
Author Information: Complete names, affiliations, ORCID IDs, and email addresses for all authors. Corresponding author must provide full contact details including institutional address and phone number.
Competing Interests Statement: Declaration of financial relationships, consulting arrangements, or other potential conflicts of interest. If no conflicts exist, state "The authors declare no competing interests."
Funding Information: List all funding sources including grant numbers. Acknowledge the role of funders in study design, data collection, analysis, and manuscript preparation.
Author Contributions: Specify each author's contribution using CRediT taxonomy (Conceptualization, Methodology, Investigation, Writing, etc.). All listed authors must meet ICMJE authorship criteria.
Data Availability Statement: Describe how readers can access underlying data. For clinical trials, include protocol and statistical analysis plan availability. Genomic data should be deposited in public repositories (GEO, SRA).
References: Format according to Vancouver style (numbered citations in order of appearance). Ensure all references are complete with author names, article titles, journal names, publication years, volume/issue numbers, and page ranges. Verify DOIs for all references where available.

Manuscript Preparation Guidelines

Formatting Requirements

Manuscripts should be prepared in Microsoft Word (.docx) or LaTeX format with the following specifications:

Double-spaced text throughout (including references and figure legends)
12-point Times New Roman or Arial font
Continuous line numbering for ease of review
Page numbers in the bottom right corner
Margins: 1 inch (2.54 cm) on all sides
SI units for all measurements (with conventional units in parentheses if appropriate)

Title Page Components

The title page should include:

Title: Concise and informative (maximum 150 characters), avoiding abbreviations
Running Title: Shortened version (maximum 50 characters) for page headers
Authors: Full names with academic degrees and ORCID identifiers
Affiliations: Department, institution, city, state/province, country for each author
Corresponding Author: Complete contact information including email, phone, and postal address
Word Count: Separate counts for abstract and main text (excluding references, tables, and figures)
Keywords: 5-8 terms from Medical Subject Headings (MeSH) when possible

Abstract Structure

For original research articles, use a structured abstract (250 words maximum) with the following headings:

Background: Context and rationale for the study
Methods: Study design, patient population, interventions, and primary outcomes
Results: Key findings with specific data (include p-values and confidence intervals)
Conclusions: Interpretation and clinical implications

Statistical Reporting

All statistical analyses must be clearly described and appropriately applied:

Specify statistical software used (name and version)
Define all statistical tests and significance thresholds (typically p < 0.05)
Report confidence intervals (95% CI) for primary outcomes
For clinical trials, include sample size calculations and power analysis
Describe handling of missing data and sensitivity analyses
For survival analyses, include hazard ratios with 95% CI

Figure and Table Guidelines

Visual elements should enhance understanding of your hepatology research:

Figures: Submit as separate files in TIFF or EPS format (minimum 300 DPI). Histopathology images should be high-resolution with scale bars. Label all panels (A, B, C) and reference them in the caption.
Tables: Create in Word or Excel (not as images). Include descriptive titles and define all abbreviations in footnotes. Use horizontal lines only (no vertical lines).
Legends: Provide detailed figure legends that allow understanding without reference to the main text. Define all symbols, arrows, and abbreviations used.
Color: Ensure figures are interpretable in grayscale. Use colorblind-friendly palettes when possible.

Ethical Considerations for Hepatology Research

Human Subjects Research

All clinical studies involving human participants must comply with the Declaration of Helsinki and obtain appropriate ethical approval:

IRB/Ethics committee approval required before study initiation
Written informed consent from all participants (or legally authorized representatives)
Patient privacy protection: remove identifying information from images and case descriptions
For retrospective studies, document waiver of informed consent if applicable
Clinical trials must be registered in recognized databases (ClinicalTrials.gov, ISRCTN, etc.)

Animal Research

Studies using animal models of liver disease must adhere to ethical standards:

IACUC or equivalent committee approval required
Compliance with ARRIVE guidelines for reporting animal research
Justification of animal model selection and sample size
Description of measures to minimize pain and distress
Statement of euthanasia methods used

Data Sharing and Transparency

We encourage open science practices in hepatology research:

Deposit genomic data in public repositories (GEO, SRA, ENA)
Share de-identified patient data when ethically permissible
Provide study protocols for clinical trials
Make statistical analysis code available upon reasonable request
Declare data availability in the manuscript

Journal of Spleen And Liver Research – Submit Paper

Submit Your Hepatology and Gastroenterology Research