Acquired haemophilia (AHA) is a rare coagulation disorder secondary to autoantibodies against coagulation factor, most commonly factor VIII with potential for life threatening bleeding episodes. We report a case of an 88-year-old female pres...
Hereditary thrombotic diseases, or inherited bleeding disorders, are a group of genetic conditions that disrupt normal blood coagulation. These diseases result from mutations in genes encoding blood coagulation factors or other regulatory pr...
π€ Authors:C. Sudlow Leland, Du Junwei, Shahverdi Kiana+ 2 more
π Abstract:
Background
Oxaliplatin, a widely used chemotherapeutic agent, is associated with hematologic toxicities such as anemia, leukopenia, and thrombocytopenia. Despite their clinical relevance, the molecular mechanisms underly...
π€ Authors:Ruben Soto, Rocio Quilodran, Manuel Najera+ 1 more
π Abstract:
This study characterizes an oncogeriatric cohort at a cancer institute, reporting tumor types, comorbidities, geriatric assessments, and treatment patterns. Findings inform service planning and individualized care for older adults with cance...
π€ Authors:Padaro Essohana, Layibo Yao, M. C. Womey Kodzovi+ 6 more
π Abstract:
Objective
Drawing up a balance sheet of 16 years follow-up of the sole case of Diamond-Blackfan anemia diagnosed in Togo with arguments of molecular biology.
...
π€ Authors:Padaro Essohana, M C Womey Kodzovi, Layibo Yao+ 3 more
π Abstract:
While highly curable in developed countries, Hodgkin's lymphoma (HL), remains a significant challenge for resource-limited ones. This study aimed to describe the profile of HL in Togo. This was a retrospective, descriptive study conducted at...
π€ Authors:G. Lu Jiajie, Pow-Anpongkul Pete, Cai Jennifer+ 2 more
π Abstract:
Lennert lymphoma (lymphoepitheloid lymphoma) is an extremely rare variant of peripheral T-cell lymphoma, not otherwise specified. Here we report a case of Lennert lymphoma diagnosed in a 57-year-old woman. She had a three-year history of wax...
A 61 years female patient with known diagnosis of the breast cancer in remission for more than 10 years has Renaudβs disease. During her work up for lupus and lupus anticoagulant which both were negative a prolonged thromb...
π€ Authors:B. Danilova Anna, A. Efremova Natalia, A. Murashkina Anna+ 5 more
π Abstract:
Background
Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tum...
π€ Authors:Tran Truc, Cai Jennifer, Ji Ping+ 1 more
π Abstract:
Background
Monoclonal gammopathy of undetermined significance (MGUS) and chronic myeloid leukemia (CML) are diseases of different lineages. The diagnosis of both MGUS and CML in the same patient is a rare occurrence and ...
In Mexico, breast cancer is the second most common site of cancer in women and in most developed and emerging countries. Incidence rates have increased in many countries, although in some, mortality has remained stable with a slight reductio...
π€ Authors:Crabtree Matthew, Ji Ping, Cindy Cai Jennifer+ 1 more
π Abstract:
Plasma cell neoplasms of the thyroid gland are uncommon. They may occur either as a primary extraosseous (extramedullary) plasmacytoma or as secondary involvement by multiple myeloma (MM). Here, we report the case of a 62-year-old female, pr...
The prostate gland is subject to various disorders. The etiology and pathogenesis of these diseases remain not well understood. Moreover, despite technological advancements, the differential diagnosis of prostate disorders has become progres...
π€ Authors:Vadehra Kumkum, Cai Jennifer, Rekha Bhuyan Rashmi+ 3 more
π Abstract:
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a recently recognized type of T-cell lymphoma that can develop following breast implants, with morphologic and immunophenotypic features indistinguishable from those of ALK-n...
Introduction
Acute leukaemia are the clonal and malignant proliferation of immature hematopoietic cells (blast), blocked in their differentiation process. There is an interaction between cancer cells and the clotting pr...
π€ Authors:Mamadou Sekongo Yassongui, Saydou Kabore, Boidy Kouakou+ 6 more
π Abstract:
This article has been retracted on 29 January 2021. VIEW THE RETRACTION NOTICE (https://doi.org/10.14302/issn.2372-6601.jhor-25-5854)
In CΓ΄te d'Ivoire, sickle cell disease affects 14% of the population. It is responsible for signific...
π€ Authors:Demiral Selcuk, Beyzadeoglu Murat, Dincoglan Ferrat+ 1 more
π Abstract:
Objective
Meningiomas are most common intracranial benign tumors comprising around one third of all intracranial neoplasms, and typically have benign and indolent nature with slow-growing behaviour. Benign meningiomas ar...
π€ Authors:Ozcelik Fatih, Keskin Umran, KΔ±lΔ±Γ§aslan Emrah+ 1 more
π Abstract:
Immune thrombocytopenia currently called under itsβ new name, immune thrombocytopenic purpura (ITP) is a disease characterized by thrombocytopenia, in which the body attacks its own platelets due to the disorders in immune system. The pathop...
π€ Authors:Nefyodov I.I., Karakosh A.J., Alufaini M.A.+ 2 more
π Abstract:
A mini-review of literature data on the mechanisms of formation of the stock of free amino acids and their derivatives in liver pathology and methods for correcting metabolic imbalance
π€ Authors:Siskos Nikistratos, Bekiari Chryssa, Poutahidis Theophilos+ 2 more
π Abstract:
WaldenstrΓΆm Macroglobulinemia (WM) is a B-cell lymphoproliferative disorder characterized mainly by uncontrolled accrual of M- immunoglobulin, secreted by malignant lymphoplasmatic cells. Mast cells interacting with malignant B-cells play an...
Prostate specific antigen (PSA) does not provide the high reliability and precision that is required for an accurate screening for prostate cancer (PCa). The aim of our study was to search for a simple, rapid, direct, preferably non-invasiv...
π€ Authors:Mamadou Sekongo Yassongui, Kabore Saydou, Dembele Bamory+ 5 more
π Abstract:
Introduction
The anti-HCV RIBA test verifies the presence of anti-HCV serum antibodies detected by the Elisa test. In CΓ΄te d'Ivoire, screening for hepatitis C is done exclusively by enzyme immunoassays. In order to reduc...
Although surgery is the main treatment for solid tumors, it could enhance the growth and metastasis of minimal residual cancer. In this review article we have discussed the perioperative changes in cancer cells and surrounding environment as...
Investigation of Antimicrobial Activity of the Extracts of the Leaves, Stembark and Root of Allanblackia floribunda: An Alternative Paradigm Shift Outcome.
Liaquat University of Medical and Health Sciences Jamshoro
Ashique Ali Arain, Syed Muhammad Ali, Madiha Shah
Vitamin -D Deficiency: A Clinical Problem Searching For Solution.