Journal of Enzymes

Submit Your Enzyme Research

Join leading researchers advancing our understanding of enzyme mechanisms, biocatalysis, and molecular enzymology

51% Acceptance Rate
21 Days Time to First Decision
60 Days Submission to Publication
Start Your Submission

Research Scope

Journal of Enzymes welcomes submissions across all areas of enzymology, with particular emphasis on three core domains:

Core Focus

Clinical/Medical Enzymology

Clinical studies clarifying enzyme biomarkers, diagnostic workflows, and enzyme-based interventions in human disease.

  • Enzyme deficiencies and replacement therapy
  • Enzymatic drug metabolism
  • Enzymes in inflammation and oncology
  • Metabolic disorders and rare genetic conditions
Core Focus

Systems-Level / Pathway Enzymology

Research mapping enzyme networks, pathway dynamics, and multi-enzyme regulation at cellular or organismal scale.

  • Pathway rewiring and metabolic control
  • Enzyme co-factor balance
  • Systems biology linking enzyme function to phenotype
  • Integrative omics with mechanistic conclusions
Core Focus

Therapeutic Enzyme Modalities

Studies exploring therapeutic enzymes including enzyme replacement, prodrug activation, and enzyme-based biologics.

  • Enzyme-mediated detoxification
  • Delivery systems and stability engineering
  • Clinical pharmacology of therapeutic enzymes
  • PEGylation and formulation optimization

Two Convenient Submission Methods

We offer two streamlined online submission options designed to make the process as efficient as possible for enzyme researchers. Choose the method that best fits your workflow and manuscript complexity.

Recommended

ManuscriptZone Portal

Our comprehensive manuscript management system provides complete control over your submission from start to publication. Ideal for researchers who want real-time tracking and direct communication with editors.

  • Auto-save functionality protects your work
  • Guided step-by-step submission workflow
  • Real-time manuscript status tracking
  • Direct access to reviewer comments
  • Secure document management
  • Revision submission and response tracking

Best for: Complex manuscripts with multiple authors, extensive supplementary materials, or those requiring revision tracking.

Submit via ManuscriptZone
Quick Option

Quick Submission Form

A streamlined alternative for straightforward submissions. Perfect for researchers who prefer a simple, fast submission process without account creation.

  • No account registration required
  • Single-page submission form
  • Fast upload for manuscript and figures
  • Immediate confirmation email
  • Suitable for standard research articles

Best for: Standard research articles, short communications, or preliminary submissions without complex supplementary materials.

Use Quick Submission Form

Complete your submission in just 15 minutes. Both methods ensure your enzyme research receives the same rigorous peer review by experts in enzyme mechanisms, protein structure, and biocatalysis.

Manuscript Types We Publish

Enzymes welcomes diverse contributions to enzymology research. Our expert editorial board evaluates each submission for scientific rigor, methodological soundness, and contribution to the field.

Original Research Articles

Comprehensive studies on enzyme kinetics, protein interactions, catalytic mechanisms, or structure-function relationships. Present novel findings with detailed methodology.

Systematic Reviews

Comprehensive syntheses of current knowledge in enzymology subfields. Cover recent advances in enzyme mechanisms, biocatalysis, or therapeutic applications.

Methods and Protocols

Novel experimental techniques, improved methodologies, or innovative approaches in enzyme research. Include detailed protocols for reproducibility.

Short Communications

Preliminary findings, rapid reports, or focused studies on specific enzyme mechanisms. Ideal for time-sensitive discoveries.

Structural Biology Reports

Protein structure determination, molecular modeling, or structure-function relationship studies. Include crystallographic or NMR data.

Mini-Reviews

Concise overviews of emerging topics or recent breakthroughs in enzymology. Focus on timely areas with significant research activity.

Pre-Submission Checklist

Ensure your enzyme manuscript meets our requirements before submission. This checklist helps streamline the review process.

  • Manuscript file ready: Word (.doc/.docx) or LaTeX format, double-spaced, line numbers enabled for review
  • Title and abstract: Concise title reflecting enzyme focus; structured abstract under 300 words
  • Figures and tables: High-resolution figures (TIFF/EPS, 300 DPI minimum); editable tables; all referenced in text
  • References formatted: Follow journal citation style; include DOIs where available
  • Author information complete: All authors listed with affiliations, ORCID IDs, and contribution statements
  • Ethics documentation: IRB/IACUC approval for human/animal studies; biosafety clearance; data availability statement
  • Competing interests declared: Financial and non-financial conflicts disclosed for all authors
  • Supplementary materials: Additional data files, protocols, or multimedia organized and labeled clearly

Peer Review Timeline

We are committed to providing timely, rigorous peer review by experts in enzymology. Our transparent process ensures you know exactly where your manuscript stands.

1

Submission Received

Your manuscript is logged into our system and assigned a tracking number. You receive immediate confirmation.

Day 0
2

Editorial Screening

Editor-in-Chief reviews for scope, quality, and adherence to guidelines. Plagiarism check performed.

Days 1-3
3

Peer Review Assignment

Manuscript sent to 2-3 expert reviewers specializing in your research area.

Days 4-7
4

Expert Review

Reviewers evaluate scientific rigor, methodology, data interpretation, and contribution to enzymology.

Days 8-28
5

Editorial Decision

Editor synthesizes reviewer feedback and makes decision: Accept, Minor Revisions, Major Revisions, or Reject.

Days 29-35
6

Publication

Accepted manuscripts proceed to copyediting, typesetting, and online publication with full Open Access.

Day 60

Average time from submission to publication: 60 days. We prioritize both speed and quality, ensuring your enzyme research reaches the scientific community quickly without compromising peer review rigor.

Why Enzyme Researchers Choose JEN

👤

Expert Enzymology Reviewers

Peer review by specialists in enzyme mechanisms, protein structure, and biocatalysis

Fast Editorial Decisions

Average 21 days to first decision - among the fastest in enzymology publishing

🌐

Immediate Global Access

Open Access ensures your research reaches enzyme scientists worldwide without barriers

💰

APC Waivers Available

Financial support for eligible authors from developing countries or unfunded research

COPE Member

Committed to highest ethical standards in scholarly publishing and research integrity

Manuscript Preparation Guidelines

Structure Your Enzyme Manuscript

Organize your research article following standard enzymology conventions to facilitate peer review and reader comprehension.

Title: Concise and specific, reflecting the enzyme focus (e.g., "Kinetic Characterization of a Novel Thermostable Lipase from Bacillus sp." not "Enzyme Study").

Abstract: Structured format (Background, Methods, Results, Conclusions), 250-300 words. Clearly state the enzyme investigated and key findings.

Keywords: 5-7 terms including specific enzymes, mechanisms, or techniques (e.g., "enzyme kinetics," "directed evolution," "biocatalysis").

Materials and Methods: Detailed protocols for reproducibility - enzyme sources, assay conditions, kinetic parameters, statistical analyses. Reference established protocols where appropriate.

Results: Present findings logically with appropriate figures (kinetic plots, structural data, activity assays). Describe enzyme behavior without interpretation.

Discussion: Interpret enzyme mechanisms, compare with existing literature, discuss implications for biocatalysis or therapeutic applications, acknowledge limitations.

Data Availability

Enzyme research increasingly requires data sharing. Include statements on:

  • Protein structures: Deposit in PDB with accession codes
  • Sequences: Submit to GenBank or UniProt
  • Kinetic data: Include in supplementary materials
  • Plasmids: Availability through Addgene or other repositories
  • Custom code/scripts: Share via GitHub or supplementary materials

Submit Your Enzyme Research Today

Join leading researchers advancing enzyme science. Choose your preferred submission method below.