Recently Published Articles
Research Gaps In Contaminants Of Emerging Concern (CECs): Routes To The Standardization Of Chemical Test Methods By GC/LC-Mass Spectrometry: A Review
Abstract:
A literature review was undertaken with a focus on 1) identifying the research gaps regarding CECs, 2) identifying the most common ones, and 3) identifying the typical analytical methods/technologies employed, for their analysis. A total of 214 papers were noted, with a total of 21 review articles (9.8%). Of this total, a surprisingly high number were from South Africa alone: 117 (54.7%), of which 44 (20.6%) reports were associated with South Africa’s Water Research Commission (WRC). The top three CECs research gaps were (decreasing rank: Number of “gaps”, %): 1) Toxicity/Risk/Impact (260, 21.5%), 2) Analysis/Tests/Methods (118, 9.8%) and 2) Future research/studies (118, 9.8%), and 3) Monitoring (89, 7.4%). The common classes of CECs that were reported on, were : (i) Chemical: pharmaceuticals, personal care products, steroids, chlorinated and brominated contaminants, PAHs, PCBs, phthalates, alkyl phenols, herbicides, organochlorine pesti...
The Impact of EDTA And Selenite on The Stability of Insulin in Cell Culture Media
Abstract:
Insulin is a frequent peptide hormone addition in serum-free mammalian cell culture media. It contributes in a variety of biological functions, including as promoting cell proliferation, cell cycle progression, and glucose uptake. However, it is unknown how stable insulin is under in vitro cell culture media treatment conditions. The instability of insulin in aqueous solutions has caused a number of issues, necessitating the development of new therapeutic strategies that can keep insulin stable and functioning. Such choices are required to accommodate updated insulin delivery guidelines as well as the storage and transportation of insulin. To preserve structural and functional integrity, protein medicines are frequently stabilized with antioxidants in aqueous solutions. In the present study, the effects of the antioxidants disodium ethylenediaminetetraacetic acid dihydrate (EDTA) and sodium selenite (Se) and their ...
A Data Mining Methodology for Detecting Conspiracy Theories from Scientific Articles: The Covid-19 Case
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The goal is to do a text mining analysis of all scientific publications and find out what journal and what aspects are studying about the conspiracy theories of Covid-19. For this purpose, all publications available in the National Center for Biotechnology Information (NCBI) database were consulted as they were peer-reviewed papers. Of all these papers, only the abstracts of each one were studied using artificial intelligence techniques to determine, for example, whether the subject is of importance depending on the journals where it has been published, and above all, what possible relationships could be extracted from the information published in them. In addition, the "Net Prevalence per Covid19" index was definedin those countries with a high value, greater campaigns should be sponsored to avoid the misinformation generated by Covid-19, although this comment should be verified in future publications. The main challenge was to unify the abstracts and for this ...
Magnitude and Trends of Chronic Liver Disease: A Retrospective Hospital Based Study in Eastern Amhara Region, Northeast Ethiopia
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A retrospective study quantifies chronic liver disease burden and trends in Eastern Amhara. It summarizes demographics, etiologies, and outcomes to inform regional planning.
Production of biodegradable polymer via graft copolymerization of gum Arabic and polyethylene glycol
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The increasing demand for environmentally-friendly materials has led to a surge in research on the production of biodegradable polymers. In this study, we investigate the synthesis of a biodegradable polymer by graft copolymerization of gum Arabic (GA) and polyethylene glycol (PEG). GA, a natural polysaccharide and PEG, a synthetic water-soluble polymer, were used as the backbone and graft monomer, respectively. The graft copolymerization was carried out using benzoyl peroxide as an initiator and performed under nitrogen atmosphere. The resulting polymer was characterized by Fourier transform infrared (FTIR) spectroscopy, Xray diffraction (XRD), thermogravimetric analysis (TGA), and scanning electron microscopy (SEM). The FTIR spectra confirmed the formation of the graft copolymer, and TGA analysis showed that the copolymer had higher thermal stability than GA. The DTA thermograms indicated two thermal events. The evaporation of water and organic polyethylene glyc...
Classification and Prioritization of Tasks in Public Administration
Abstract:
A large volume of data is being generated in public administration and it is necessary to develop new computational methodologies to classify and analyze it to do a better analysis and decision making. For this reason, the goal of this paper is to present a computational methodology that allows classifying and prioritizing a series of complaints using Artificial Intelligence techniques. To test this model, we generate 600 complaints in four sectors of the public administration to prove the concept. Later, we calculated the tree decision with the help of the Confusion Matrix, and finally the Priority Matrix (based on the Eisenhower model) allows setting priorities on the complaints, and offers the possibility of delegating and even postponing the response to them. In this way, it is possible to prioritize the complaints made in the public administration.
Sophomoric and Skeletal-Chondroblastoma
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A case commentary discusses a skeletal chondroblastoma with atypical features. It highlights imaging, pathology, and management considerations.
Dogonyaro-Leaf-Extract as Inhibitor for Aluminum Corrosion in Acid
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Background of this paper investigates dogonyaro-leaf-extract as inhibitor for aluminum corrosion in 0.3-M hydrochloric acid, and its acceptability as original. In the methods, the extract was analyzed for phytochemicals and corrosion test performed on aluminum sheet before immersion in acid incorporated extract. Electrochemical Impedance Spectroscopy (EIS), tests were performed over frequency of 100 KHz–10 mHz and 10 mV peak to peak perturbation amplitude to obtain the corrosion potential. Tests were run at 30oC ± room temperature in aerated quiescent solutions. In weight loss method, coupons were suspended in aerated solutions before immersion in 20% mixture of sodium hydroxide and zinc dust to stop further corrosion. Morphology of the mirrorlike finished arid surface aluminum was measured with scanning electron microscope SEM. In the results, various phytochemicals were observed; significant effect of incorporating inhibitor on EIS data recorded and...
Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients
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Cachexia is highly prevalent in cancer patients and is responsible for as much as 20% of all cancer deaths. Nevertheless, there is little emphasis on cachexia in routine clinical practice. This study looks at the efficacy and tolerability of a protein and energy-dense nutritional supplement with immunonutrients on cachexia in cancer patients. This was a three-month, prospective, open-label study of patients undergoing radiotherapy and/or chemotherapy for head and neck or gastrointestinal or lung cancer. Efficacy endpoints were mean change in muscle strength, acute phase proteins (albumin and pre-albumin), C-reactive protein (CRP) levels, weight, Glasgow prognostic score (GPS), and nutritional status at the end of the study period.
The Tinged Parchment-Cutaneous Mastocytosis
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A clinical image and brief discussion of cutaneous mastocytosis describe presentation, dermoscopy, and diagnostic clues. The note underscores when to evaluate for systemic involvement.