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The Effect of Aqueous Extract of Ocimum gratissium (Linn) on 1, 2 - Dimethyl Hydrazine induced Colon Cancer in Male Wistar Rats

Abstract:

Background

Colon cancer is one of the leading causes of cancer death world-wide. There is a steady increase in incidence over the past four decades in developing countries. This has been partly attributed to increasingly low intake of vegetables among other causes.

Aims

Therefore this study aims to evaluate the protective effect of aqueous extract of Ocimumgratissimum (OG) leaves (a staple vegetable) on experimental model of colon carcinogenesis induced with 1, 2 Dimethylhydrazine (DMH). This is compared with celecoxib (a cyclooxygenase-2 inhibitor) which is used in the chemoprevention of colon cancer.

Methods

Sixty adult male Wistar rats were randomly divided into six groups: A to F, n=10. Gr...

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Term Paper on The Nature of Cyber Crime and Cyber Threats: A Criminological Review

Abstract:

Cybercrime is one of the fastest-growing criminal activities in contemporary age. The first recorded cybercrime happened in France in the year 1820. It was not as sophisticated as cybercrime we know in our world today, but, still, that was a crime. Cybercrime has evolved globally as the online platform is progressing. While progress is made in the battle against cybercrime there still remains a wide gap in the consistency of laws across international borders. The main objectives of this study are to explore the nature of cybercrime in developing countries, find out the cyber threats for terrorist activities and explain cybercrime and threats from criminological aspects. This is a descriptive study which is based on secondary data. This study is based on previous researches & studies. this paper discusses the nature of cybercrime in developing countries. It could allow developed countries to understand better the national and international effects of that cyber...

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The Genetic Multiplicity- Multiple Endocrine Neoplasia type I

Abstract:

Multiple endocrine neoplasia type 1 (MEN1) is a syndrome emerging from characteristic mutations of  MEN1 gene with concurrently enunciated  multiple endocrine and tumours and associated non-endocrine neoplasm. Previously designated as Werner’s syndrome, MEN1 syndrome denominates genomic mutation within  chromosome 11q13 or a  tumour suppressor  gene with a distinctive protein product nomenclated as “menin”. MEN1 syndrome demonstrates an autosomal dominant pattern of disease inheritance where genomic mutations delineate  a comprehensive (100%) disease penetrance. MEN1 gene was initially identified in 1997 upon chromosome 11q13. Although twelve genetic mutations were primarily identified, currently beyond eighteen hundred genomic mutations are scripted12. MEN1 syndrome is comprised of diverse combination of twenty or more endocrine and non-endocrine t...

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Anatomical Variants of the Placenta in Sudanese and their Relation to the Neonatal Outcome

Abstract:

Background

In recent years great attention has been focused on the structural and histological structures of the placenta and the umbilical cord due to their vital roles in fetal development and neonatal survival. While extensive studies have been documented in this area in the developed world, there is very little published information about the morphological variations that occur in human placenta in Sudan. Therefore, this study was designed to evaluate the structural variations in placental indices and its relation to neonatal outcome.

Methods

A prospective hospital - based study conducted in Wad Madani Maternity Teaching Hospital Department of Obstetrics and Gynecology between July 2014 and March 2018.

Results

Mean place...

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Arbuscular Mycorrhizal Biofertilizers Sources in the Potato (Solanum Tuberosum) Plant show Interactions with Cultivars on Yield and Litter-bags Spectral Features

Abstract:

Four strains of Arbuscular Mycorrhizal (AM) biofertilizer fungi, combined with two potato cultivars, were in-field tested in a four-replicate arrangement in a factorial experiment. As far as general combinability is concerned, cv. Agria was more responsive to different inocula (yield +5.56%, P 0.02) and to  two strains in particular (+8%). On the other hand, the results with Innovator, a cultivar that yields 33% less than Agria, showed a significant reduction in the number of tubers for three AM strains, thus proving a clear genetic Biofertilizer * Cultivar interaction. The study of hay litter-bags has shown a high NIR spectral fingerprint for the Cultivar factor (81%), while the Inoculation factor showed a higher spectral fingerprint in Agria (76%) than in Innovator (65%). The Substrate Induced Respiration predicted from the NIR-SCiO spectra of the litter-bags was significantly increased after inoculation (+6.3%, P 0.04), but appeared lower for Agria ...

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Prevalence of Overconsumption of Salt and its Determinants – The Case of Southwestern Rural China

Abstract:

Aim

Overconsumption of salt contributes to hypertension and increases the risks of cardiovascular diseases. Most studies that investigated salt intake by applying the Health belief model (HBM) have focused on urban settings. This study aims to identify the prevalence of salt overconsumption (>6 g per day) in a rural village in Southwestern China and to determine the association between knowledge regarding salt consumption/HBM constructs and salt overconsumption behavior among village residents.

Methods

Inthis cross-sectional study, 79 adults aged 18 years and above were interviewed using household-based and face-to-face questionnaires. Salt intake was measured using an electronic balance in accordance with a previous protocol.

Re...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://oap-onlinejournals.org/international-journal-of-nutrition/article/1255">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Study of Antioxidant and Membrane Resistant Peculiarities of a New Cyan Containing Lactone in Membranes of Hepatocytes with Sarcoma-45</h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <p>The antioxidant and membrane resistant peculiarities of a new derivative (2-cyan-3,4,4-trymethil-2-buten-4-olyd - CTBO) of cyan containing unsaturated lactones have been studied in membranes of hepatocytes with Sarcoma-45 <xref ref-type="bibr" rid="ridm1843951884">1</xref>.</p> <p>The results of our previous research <xref ref-type="bibr" rid="ridm1843951884">1</xref><xref ref-type="bibr" rid="ridm1844018764">2</xref><xref ref-type="bibr" rid="ridm1844032084">3</xref> showed significant changes of phospholipid (PL) exchange in hepatocytes of microsomal membranes at experimental animals vaccinated with Sarcoma-45 tumor strain. It is manifested in significant changes of quantitative and qualitative contents of membrane phospholipids separate fractions, increase of cytotoxic lysophospholipids (LPCs), phosphatidylinositol (PI) and phosphatidic acid (PA) levels, significant decrease of phosphatitylcholines (PC) and sphingomyeline (SP) contents, statistically si...</p> <a class="btn btn-primary blue-btn text-uppercase my-4" href="https://oap-onlinejournals.org/enzymes/article/1254">Read Article</a> </div> </div> <div class="col-md-6 mb-3 aos-item aos-init " data-aos="fade-up"> <!-- child-div --> <div class="article-section p-3"> <h4 class="article-title title-border pb-3"> Interest of Confirmation Tests in the Diagnosis of Viral Hepatitis C to Blood Donors in Abidjan-Côte d'Ivoire </h4> <h4 class="article-title fw-700">Abstract:</h4> <p><abstract> <sec id="idm1849541828"> <title>Introduction

The anti-HCV RIBA test verifies the presence of anti-HCV serum antibodies detected by the Elisa test. In Côte d'Ivoire, screening for hepatitis C is done exclusively by enzyme immunoassays. In order to reduce the number of HCV positive blood donor exclusions on ELISA, we conducted this study which aimed to demonstrate the value of the RIBA test in confirming diagnosis of viral hepatitis C to blood donors.

Methods

Our study, which took place from 02 to 23 February 2008 in the laboratory of Abidjan NBTC, focused on 200 sera of blood donors anti-HCV positive (Elisa test) selected according to the ratio. The DECISCAN HCV PLUS confirmation test of BIORAD was used.

Results

Among the 200 HCV samples positive by EIA, 49%...

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Performance of New and Old Short-Seasoned Arachis Hypogea (Groundnut) Varieties Under Same Agronomic Practices

Abstract:

Performance of three newly released short-seasoned (Nsinjiro, Chitala and JL11) were evaluated against old (Nyanda, Illanda and Tern) groundnuts varieties under same agronomic practices. A field experiment laid in a randomized complete block design (RCBD) with three replicates was done. Varieties were evaluated for days to 50% emergence, 50% flowering, days to physiological maturity, pod and seed yield, and shelling percentage. There were no significant difference in the days to 50% emergence among all varieties but significant difference (p ˂ 0.05) were observed on days to 50% flowering. JL11 and Tern took shortest (90 days) and longest (120 days) time to physiological maturity respectively. Chitala had highest (3.804t/ha) and Tern had lowest (3.020t/ha) seed yield. Jl11 had highest (83%) and Nyanda least (68%) shelling percentage. Results showed that the new varieties out-performed the old varieties in all measured parameters. Therefore, resource constrained fa...

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Structuredness as a Measure of the Complexity of the Structure and the Role of Post-Dissipative Structures and Ratchet Processes in Evolution

Abstract:

As shown earlier, the algorithmic complexity, like Shannon information and Boltzmann entropy, tends to increase in accordance with the general law of complification. However, the algorithmic complexity of most material systems does not reach its maximum, i.e. chaotic state, due to the various laws of nature that create certain structures. The complexity of such structures is very different from the algorithmic complexity, and we intuitively feel that its maximal value should be somewhere between order and chaos. I propose a formula for calculation such structural complexity, which can be called - structuredness. The structuredness of any material system is determined by structures of three main types: stable, dissipative, and post-dissipative. The latter are defined as stable structures created by dissipative ones, directly or indirectly. Post-dissipative structures, as well as stable, can exist for an unlimited time, but at the micro level only, without energy in...

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