Research Topic · Peer-Reviewed

Animal Model

An animal model is a non-human organism used to study biological processes, disease mechanisms, and candidate therapies under controlled conditions that approximate human or veterinary physiology. Models range from invertebrates such as Drosophila to rodents and larger mammals, and are selected for genetic tractabil…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 26× across the literature 🗓 Reviewed June 2026

Overview

An animal model is a non-human organism used to study biological processes, disease mechanisms, and candidate therapies under controlled conditions that approximate human or veterinary physiology. Models range from invertebrates such as Drosophila to rodents and larger mammals, and are selected for genetic tractability, physiological similarity, or the ability to recapitulate a specific disease phenotype. They are classified as spontaneous, induced, genetically engineered, or xenograft models, and underpin preclinical research by enabling mechanistic investigation, pharmacological testing, and safety evaluation before clinical translation. Validity depends on construct, face, and predictive relevance to the condition under study, and rigorous models are essential to drug discovery, immunology, oncology, and neuroscience, while ethical and welfare considerations govern their use. Research relevant to this area examines learning and memory in a longevity model using Ames dwarf mice, imaging-agent development in tuberculosis models, cellular and molecular biomarkers of probiotic activity, in silico, in vitro, and in vivo drug-design pipelines, sleep biomarkers in a chronic-stress animal model, laryngeal tissue engineering in a pre-clinical model, ocular models of intraocular pressure, and xenotransplantation studies of mast-cell populations. This peer-reviewed literature reflects the design, validation, and application of animal models across biomedical and translational research, situating model systems within the broader study of comparative and experimental biology.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 26 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Animal Model, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Primates.

Journal editorial board
Arthur Saniotis · Australia Vincent L Bels · France

This page summarises published research for orientation; it is not medical or professional advice.