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Dec 2020 DOI 10.14302/issn.2644-1101.jhp-20-3637
How human understand and represent concepts is always a hot topic in cognitive psychology. According to the conceptual metaphor theory 12, understanding and representing abstract concepts rely on concrete concepts via metaphoric mappings. In this review, we discussed three core issues with the aim to have a comprehensive understanding of conceptual metaphors. First, I describe the underlying process of metaphoric mappings. Lakoff and Johnson (1999) 2 put forward that the source domain (concrete concepts) can be used to represent the target domain (abstract concepts). The metaphoric mappings from source domains to target domains are characterized as image schemas, which structure and provide sensory-motor grounding for abstract concepts. Then, I concerned on the directionality (the second issue) and automaticity (the third issue) of metaphoric mappings. According to conceptual metaphor theory, metaphoric mappings have the directionality from the concrete domain to the abstract domain, which is an automatic and obligatory process with neither effort nor awareness. However, directionality and automaticity were debated by recent research. In this article, by focusing on the three important issues I provided a comprehensive review which would help deepen our understanding about the nature of metaphoric mappings.
Oct 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3597
An opinion piece argues that coherent medical concepts should guide pandemic response over political narratives. It stresses evidence-based decision-making, transparent risk communication, and iterative learning guided by clinical evidence.
Apr 2020 DOI 10.14302/issn.2692-5257.ijgp-20-3299
The coronavirus disease 2019 (COVID-19) pandemic is something new that baffles us. The dominant health model and the theory that supported it until before COVID-19 are refuted or invalidated by observing the current tragically situation, which also implies lasting changes in that new medical model. Consequently, once the urgency of the epidemic is over, the conceptual and organizational building of medical care can no longer be rebuilt in the same way. Based on the COVID-19 experience, it is necessary to rethink what kind of knowledge can emerge. Some of the concepts with clinical-epidemiological implications that have to be re-evaluated since the COVID-19 pandemic are: 1. Large epidemics or changes do not arise from an event similar to the "Big Bang", but rather they develop slowly and underground, so a surveillance system must be instituted; 2. Re-evaluate what we understand by "evidence-based medicine"; 3. Patient-centered care is inadequate and must be replaced by community-centered care; 4. Telecare and changes in the organization of consultations; 5. Hospitals and health centers are "biological bombs" that act as vectors of disease and must change their architecture, organization and use; 6. The end of the nursing home model; 7. Change of habits; and 8. Social media can democratize information and help communities organize.
Dec 2024 DOI 10.14302/issn.2470-0436.jos-24-5322
Studies show that individuals with limited health literacy skills experience worse health outcomes in a multitude of chronic diseases including glaucoma. These patients have poorer compliance, worse disease understanding and greater disease progression. The main purpose of our study was to evaluate the knowledge about glaucoma basic concepts in patients with this disease. A 24 question survey was given to patients followed by the glaucoma department, by phone or in person. Epidemiological data and personal therapeutic regimens were collected as well as data concerning the pathophysiology, treatment and prognosis of the disease. Survey responses were obtained from 79 patients with a mean age of 72 years old. Most of the patients had a low education level. The majority of patients could not enumerate glaucoma risk factors (74.5%), their glaucoma type (94.9%) or the best glaucoma definition (57%). However, they were able to relate the disease to a high IOP (75.9%) and the possibility of it leading to blindness (96.2%). We believe that patients, when observed in their glaucoma appointments, tend to retain information related to the prognosis and consequences of the disease and not focus on the understanding of its pathophysiology, causes and mechanisms, which may reflect their concern about their own future. However, this may lead to some misconceptions about the definition of glaucoma and specially about what can cause this disease. Some investment should be done to improve health literacy in the glaucoma population, with appropriate language and handed material.
Feb 2024 DOI 10.14302/issn.2766-8681.jcsr-24-4897
Introduction The arrangement of teaching content to relate to or unite concepts that are regularly taught in different academic courses or departments is referred to as integration of teaching. It simply refers to creating links between theoretical knowledge and actual application. Teaching the fundamental sciences in separate blocks prevents students from having the opportunity to connect and integrate their newly acquired knowledge. Objectives To evaluate the effectiveness of Integrated teaching method over traditional teaching and perception of students towards integrated method among first MBBS students Methodology The total of 62MBBS first year students are randomly divided into two groups, with 31 in each group. Group A is subjected for Conventional teaching and Group B for Integrated teaching method in the same topic. Among the 2 sessions one session is Horizontal and other is Vertical method of integrated teaching have been implemented. Finally, an evaluation test was conducted for both the groups and the mean marks obtained by the students were analyzed by using SPSS software version 17. Student’s perception towards this method was evaluated by pre-validated feedback questionnaire and analyzed. Results The mean marks (outof40) obtained by Group B (Conventional teaching) is 13.82 and by Group A (Integrated Teaching) is 31.18. So, the marks obtained by students after integrated method were found to be higher than the other group which underwent conventional teaching and this difference was found to be statistically significant (P <0.0001). Discussion and conclusion In comparison to the typical conventional method, integrated teaching has been found to be a more successful mode of instruction in terms of students' performance and assessment exams.
Mar 2022 DOI 10.14302/issn.2379-7835.ijn-22-4120
We are experiencing years of profound cultural revolution. New insights into the microbiota upset concepts in physiology, medicine, and nutrition. The role of the microbiota for our health is increasingly evident. We are increasingly certain that our health depends on that of the microbiota, or, rather, on its strength in controlling the physiology of body organs, the mechanisms of repair and protection. It is not so much a pathogen that makes us fall ill, but a reduced ability to protect and repair ourselves from damage produced by pathogens that affect us continually. Current knowledge leads us to a new medicine aimed at curing the microbiota so that it can (come back to) take care of us. In this new medicine, food rediscovers a fundamental role, since it is the best way to communicate with the microbiota, to modulate and strengthen it. And it is curious how the most recent acquisitions bring us back to the past, to an ancient medicine, which we had forgotten after the discovery of drugs, imagined capable of acting on complex pathogenetic mechanisms. By acting, more simply, on the microbiota we can activate powerful endogenous mechanisms, which keep us healthy, when we are, more powerful than any drug we can invent. Now there is nothing left to do but apply the new knowledge.
Feb 2022 DOI 10.14302/issn.2379-8572.joa-22-4072
This translational paper discusses differentiation‑stage factors from zebrafish embryos as epigenetic regulators with potential to reverse neurosensory hearing loss. It outlines experimental evidence, delivery concepts, and research gaps.
Oct 2021 DOI 10.14302/issn.2690-0904.ijoe-21-3966
The impact of the environment on the development of non-communicable chronic diseases has gained prominence in recent years. In this context, a new chemical exposure assessment strategy is needed that is capable of revealing multiple exposures, as well as reflecting the cumulative interaction between such environmental contaminants in the biological system. From this perspective, metabolomics emerges as a promising tool in this field of knowledge, since it is able to identify changes in metabolism and/or gene expression resulting from exposure to environmental factors. The aim of this study was to describe important concepts, as well as the steps that permeate the metabolomics analysis, and also to present some relevant works with the application of metabolomics in the assessment of chemical exposure. A literature review showed a significant increase in the use of metabolomics in environmental toxicology in recent years. This increase is mainly due to advances in analytical techniques and the improvement of data processing tools. However, this field of investigation remains little explored, especially with regard to the study of toxicity associated with chronic exposure to low levels of chemical agents. Thus, it is urgent that omic biomarkers can be used as a tool for decision-making, especially with a view to protecting, diagnosing and recovering human health.
Oct 2020 DOI 10.14302/issn.2768-0207.jbr-20-3568
The Coronavirus emergency represents an epochal challenge for all world health organizations. In these times of profound destabilization of healthcare organizations, become urgent some thoughts on how to deal with the organization and re-engineering process as well as on concepts, relatively new, such as "resilience" and "business continuity". The company management need having to predict, design and plan a profound process of change in their Clinical and Corporate Governance. With the implementation of phases 2 and 3 of management of the pandemic and the coexistence of doctors and citizens with the new Coronavirus, it has become a priority to develop territorial models of assistance to established or suspected Covid patients, starting with the creation of monitoring networks based on the model of the “sentinel” general practitioner. One of the main concerns of Healthcare, since the beginning of the Covid-19 emergency has been to get closer to the citizen-patient. It is therefore necessary to find stimuli to restart with new methods of care, new health and social-health services, moving the current care paradigm for Covid-19 from the hospital to the territory, optimizing the constituent elements of the districts, primary care and general practice in a multidisciplinary approach.
Aug 2020 DOI 10.14302/issn.2474-9273.jbtm-20-3497
This paper explores the two major preventive concepts of the unpredictable life-threatening viral infection caused by Coronavirus that is ravaging the entire world from the beginning of the year 2020, as it pertains to mental health. Through scientific consultations, the expectation is that effective vaccine for the Coronavirus disease-2019 (COVID-19) may not come into the market this year. Two (among others) preventive measures, namely Social Distancing and Quarantine are suggested by the World Health Organization (WHO). Using the principle of explorative research, this study established the flipside of quarantine and social distancing from the metal health perspective. It was discovered that there is a relationship between a long period of self-isolation and a high probability of concerned persons having anxiety, stress, and depression, which gradually leads to mental and emotional health issues. Consequently, mental health affects the overall health and affects how we handle different situations during the Covid-19 pandemic. By considering this important matter, this article recommended different ways to improve mental health during the pandemic in the quest to keep oneself away from psychological issues arising due to the Covid-19 situation.
Jan 2020
A new dietary approach used to lower urea levels in chronic renal failure, and thus simulating dialysis has been recently described. This approach has been increasingly called intestinal or dietary dialysis. The aim of this paper is to describe the emerging evidence, principles, and concepts related to intestinal dialysis.
Apr 2019 DOI 10.14302/issn.2639-3166.jar-19-2732
The objectives of this study were to assess the Quality of Agricultural Graduates, employers’ perceptions of the employability and skills. A descriptive, analytical statistics, multistage random sampling method was adopted. Where two types of questionnaires were distributed to the Graduates and institutions associated with Sustainable agriculture (SA). The collected data was analyzed by Statistical Packages for Social Sciences (SPSS). The results revealed some respondents began higher education in Arabic (66.7%), while others in English (33.3%). The respondents faced with difficulties in understanding the courses due to teaching methods (36.7%), language (33.3%), and curriculum (30%). The result indicated some respondents (56.7%) do not have back ground about (SA). The respondents in the Ministries of Agriculture assessed the Graduates in regard to agricultural skills, and confidence to perform duties as fair (10%), and good (23.3%), but, for reliability, managerial skills, tactic and ability to participate in forums as fair (6.7%). Good (27.7%), fair (3.3%), and good (30%) respectively. Assessment of the Graduates at Research Centers, were assessed in relation to Research methodology, statistical analysis, and writing scientific papers as good (40 %,).While for Software skills as excellent (100%), and for Agricultural Technology Transfer as very good (80%). While; the respondents from Faculties of Agriculture, assessed the Graduated for practical skills, teaching ability, skills of writing scientific papers, participation in workshops and seminars as good (93.3%), very good (6.7%), fair (6.7) and very good (33.3%), respectively. The Graduates’ quality is below the expectations. Based on the above findings, the study recommends the review of the whole educational system, Faculties of Agriculture to include the concepts of sustainable agriculture in their curriculum and give high consideration to practical part. In the same context, further study is recommended including the whole Country.
Jan 2019 DOI 10.14302/issn.2473-1005.jdoi-19-2577
The article discusses biomechanical principles underlying tooth support and hydrodynamic equilibrium. It considers periodontal ligament behavior, load distribution, and fluid dynamics, linking basic science concepts to clinical implications.
Dec 2018 DOI 10.14302/issn.2379-7835.ijn-18-2501
In the last few years, gut microbiota has been identified to be an essential mediator in health and disease. In fact, it interacts with various organs and systems in the body, including brain, lung, liver, bone, cardiovascular system, and others. Microbiota-derived metabolites such as the short chain fatty acid (SCFA) butyrate are primary signals, which link the gut microbiota and physiology. Then, the findings on the roles of microbiota profoundly change not only the key concepts of biology and medicine, but also of nutrition. In fact, it is currently evident how the main task of nutrition is not to nourish us, but to maintain a comfortable environment for the intestinal microbiota. In this way, it works in symbiosis with us, correctly controlling the functioning of the organs, the physiological parameters and the cellular regenerative processes. It is also evident that the strength of reparative processes correlates with the ability of digestive system to process complex foods, which increases during weaning, a period of time in which the diversity of bacterial strains increases. Therefore, a task of food is to keep trained the digestive system, to which it corresponds an high microbiota diversity. Elderly leads to reduced microbiota diversity to which corresponds an intestinal frailty, responsible for the frailty of the elderly. In conclusion, a correct diet may not only keep us in good health but may also guarantee us longer longevity.
Nov 2018 DOI 10.14302/issn.2640-690X.jfm-18-2485
The transcendence of the doctor-patient relationship is given by the confirmed fact of its influence on the results of health care. Several models of doctor-patient relationship can be described, but evidence of improved compliance, satisfaction and recall of physician information has been found in patient-centered consultations. Since these concepts of doctor-patient relationship and patient-centered consultation have multiple facets, they are complex to understand and teach. Using a metaphor is a tool that can be useful in these situations. We could say that the "good" doctor-patient relationship is a process where an "alliance" is created: a process in which the doctor adapts to the rhythm of the patient and little by little can help him move towards healthier scenarios; that is, detect "what dance the patient dances and like a good dancer, take a step back, another forward, dancing and pacing with the patient. But there is not a single type of "good" or "adequate" doctor-patient relationship; there is not "a single dance that the patient dances". If "the doctor has to dance with the patient", he has to know that there are many types of dance! The doctor will have to dance dances such as Cha-Cha (which has to be slow or very fast to dance), the Mambo (where the music is faster and the rhythm more complicated - the relationship with an urgent patient); the Merengue (which is danced like walking - informal doctor-patient relationship); el Pasodoble (that you have to dance with a haughty air, but not with rigidity -synchronizing assertiveness and empathy); The Salsa (where you have to learn the basic step separately - discontinuity of the doctor-patient relationship), among others.
Sep 2018 DOI 10.14302/issn.2377-2549.jndc-18-2224
This paper describes the theoretical foundations for the electric power and hydrogen generator that functions with zero energy input without violating the laws of thermodynamics. This generation system is a combined energy cycle consisting of the H2O=H2+1/2O2 reduction reaction performed by the water electrolytic cell and the H2+1/2O2=H2O oxidation reaction performed by the fuel cell. This electrolytic method differs from the conventional electrolytic scheme in that if a quasi-static process is assumed, so that the theoretical power requirement is only 17% of the total energy required. This method performs electrostatic-to-chemical energy conversion by electrostatic-induction potential-superposed electrolytic scheme. If this electrolytic cell that delivers the pure stoichiometric H2-O2 mixture is combined with a fuel cell to form an energy cycle, then this may lead to the concepts of a hydrogen redox electric power generator and a hydrogen redox hydrogen generator that use alkaline water electrolyte or solid polymer electrolyte membrane (PEM) for both electrolytic cell and fuel cell. In the power generator, part of power delivered by the fuel cell is returned to the electrolytic cell, and the remainder represents the net power output. According to calculations based on data from the operational conditions for commercially available electrolytic cell and fuel cell, more than 70% of the power delivered from the fuel cell can be extracted outside the cycle as net power output without the use of any external source of energy.
Feb 2018 DOI 10.14302/issn.2578-8590.ipj-17-1919
A reflective piece touches on core physiological concepts and experimental approaches, linking basic mechanisms to clinical insight and education.
Feb 2018 DOI 10.14302/issn.2637-6075.jpae-17-1868
An ecological study was conducted on termites located at the new site of Ndola International Airport in Zambia. The aim of this study was: (a) to assess the distribution pattern of different sizes of termite mounds located at the site, (b) to investigate the interior geometrics of termite mounds, (c) to determine the colony sizes of termites per each mound found at the site and (d) to provide technical expertise on the different termite preventive methods used on new buildings. Methods Using an aero-drone fitted with a camera, aerial surveys were conducted to capture and evaluate the spread of differently sized mounds at the site. Mathematical models were used to calculate the volume and number of nests contained in each mound. The colony sizes were captured and recorded per each mound. Analysis Multivariate statistical analyses were performed using SPSS, to compute a two way ANOVA table for comparison of p-values involving the colony sizes and the volumes of nests for small and big mounds. The ratios affecting these volumes were also calculated. Results The total of 1,880 termite mounds was captured spreading at an average of 14 mounds/ 1km2. Results further showed that 65% of total mounds were actively housing termites while 32% were virtually deserted. The 3% balance of mounds were occupied by rodents, ants and snakes, respectively. Progression on the volume of nests in bigger and smaller mounds, significantly tallied with the size of mound at p < 0.0121 and p < 0.0346, respectively. Similarly, the colony size of termites in small and larger mounds was also significant at p < 0.002 and p < 0.001, respectively. The nest volume ratios of small, medium and larger mounds were also markedly increasing with the size of mound at 1:8.7-small, 1:32.8 medium and 1:1, 098.6-large, respectively. Conclusion Not every existing termite mound is occupied by termites; the size of nest was directly related to the size of mound; the size of colony concurrently increased with that of the volume of nest. This study unravels some intriguing and conflicting suggestions that smaller mounds can still have larger colonies underground and vice versa. Furthermore, this study is the first in Zambia to combine the concepts of termite habitat geometrics and infrastructural protection.