Research Topic · Peer-Reviewed

Monoclonal Antibodies

Monoclonal antibodies are identical antibody molecules produced from a single B-cell clone, engineered to recognise and bind one specific antigenic target with high precision. Their defined specificity makes them powerful tools in diagnostics, research, and therapeutics, where they neutralise pathogens, block signal…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 72× across the literature 🗓 Reviewed June 2026

Overview

Monoclonal antibodies are identical antibody molecules produced from a single B-cell clone, engineered to recognise and bind one specific antigenic target with high precision. Their defined specificity makes them powerful tools in diagnostics, research, and therapeutics, where they neutralise pathogens, block signalling pathways, or flag cells for immune attack. A central principle is the isolation and generation of antibodies against defined targets, illustrated by single-chain variable fragment antibodies raised against particular receptor complexes, which extends antibody technology to molecules such as neurotransmitter-receptor heteromers. In infectious disease, antibody-based strategies include the use of neutralising antibodies and convalescent immune plasma, while immunoassays and immunogenomic approaches employ antibodies for the monitoring of cancer and infection. In oncology, therapeutic antibodies that block immune-checkpoint pathways, such as the programmed cell death protein-1 axis, are used to treat malignancies including melanoma, and proteomic methods track cellular responses to antibody-directed treatments. Antibodies also serve experimental roles in detecting proteins, characterising cellular senescence, and assessing immune responses to vaccination. Research in this area develops and isolates antibodies of defined specificity, applies them to diagnosis and immunomonitoring, and evaluates their therapeutic use across cancer, infectious disease, and other conditions where targeted molecular recognition is required.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 72 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Monoclonal Antibodies, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Migraine Management.

Journal editorial board
Jing Xiang · United States Frederick Freitag · United States Yohannes W. Woldeamanuel · United States

This page summarises published research for orientation; it is not medical or professional advice.