Overview
Renal failure, also termed renal insufficiency, is the loss of the kidneys' capacity to adequately filter waste products, regulate fluid and electrolytes, and maintain acid-base balance, leading to the accumulation of toxins and metabolic disturbance. It is classified as acute, with a rapid and potentially reversible decline in function, or chronic, with progressive and often irreversible loss culminating in end-stage disease. Consequences include hypertension, electrolyte imbalance, anaemia, and cardiovascular complications, and management ranges from addressing reversible causes to dietary therapy, pharmacological treatment, dialysis, and transplantation. Research collected here reflects these dimensions, including a dietary intestinal-dialysis approach to chronic renal failure, retroperitoneal fibrosis as a cause of acute renal failure, cardiorenal signalling pathways in heart failure, and the nephrotoxicity of iodinated radiographic contrast agents. Further contributions examine polycystic kidney disease, anaemia and hyperoxaluria, transplant complications and kidney function, dipper and non-dipper hypertension by chronic kidney disease stage, and the molecular correlates of anaemia in chronic kidney disease. Together these peer-reviewed studies span the causes, complications, and management of acute and chronic renal failure, including the renal-cardiovascular interface and renal replacement strategies.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 12 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Rupam Saha et al. · 2025 · Medicine in Novel Technology and Devices
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Ibrahim Halil Kenger et al. · 2025 · Journal of Applied Toxicology
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Yuping Zhang et al. · 2025 · Biomaterials
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2025 · Journal of Applied Toxicology
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2025 · Biomaterials
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2025 · Medicine in Novel Technology and Devices
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Hajin Kim et al. · 2024 · Electronics
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2024 · Electronics
A sample of recent works citing this journal's research on Renal Failure, linking to each citing work.