Research Topic · Peer-Reviewed

Molecular Markers in Cancer

Molecular markers in cancer are measurable biological molecules whose presence, abundance, or alteration provides information about the development, diagnosis, prognosis, or treatment response of a malignancy. They include mutated genes, altered proteins, epigenetic modifications, and circulating nucleic acids detec…

Curated from this journal's research 📚 8 peer-reviewed articles cited Cited 25× across the literature 🔖 ISSN 2572-3030 🗓 Reviewed July 2026

Overview

Molecular markers in cancer are measurable biological molecules whose presence, abundance, or alteration provides information about the development, diagnosis, prognosis, or treatment response of a malignancy. They include mutated genes, altered proteins, epigenetic modifications, and circulating nucleic acids detectable in tissue, blood, and other body fluids. A central category is genetic and somatic mutation markers, such as variants in tumour-suppressor genes like TP53 and BRCA1, whose functional and structural characterisation distinguishes pathogenic changes from variants of uncertain significance. Epigenetic biomarkers, including DNA methylation and chromatin changes, are increasingly applied to cancers of the head and neck and elsewhere to refine classification and early detection. Circulating microRNAs measured in plasma can correlate with disease progression, immune-checkpoint status, and overall survival, exemplifying minimally invasive liquid-biopsy approaches. Oncofoetal antigens and tumour-associated proteins such as alpha-fetoprotein serve as serological indicators, while viral associations, as seen with Epstein-Barr virus in gastric carcinoma, link infectious agents to molecular signatures of disease. Immunoassays and emerging immunogenomic methods extend marker-based monitoring across oncology and infectious disease. By integrating mutational, epigenetic, protein, and nucleic-acid signals, molecular markers underpin diagnosis, risk stratification, therapeutic selection, and surveillance, supporting the move toward precision and personalised cancer medicine across diverse tumour types.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2018

Epigenetic Biomarkers in Head and Neck Cancer 

Gupta ShilpiCorresponding author
Stem Cell and Cancer Research Lab, Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, Sector-125, Noida-201313, India.
Cancer Genetics And Biomarkers Cited by 11 doi:10.14302/issn.2572-3030.jcgb-18-2428

How this research is being cited

The 8 articles above have been cited 25 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Molecular Markers in Cancer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Cancer Genetics And Biomarkers (ISSN 2572-3030).

Journal editorial board
Dr. Charlie Gourley · United Kingdom Dr. Xinyu Chen · United States Dr. Guru Prasad Maiti · United States

This page summarises published research for orientation; it is not medical or professional advice.